Step 2

Oncology 1

A 75 year old woman with a history of smoking and Type 2 DM is unfortunately diagnosed with metastatic breast cancer which is Her2 positive. She is eager to start the recommend therapy but is worried about the side effects. Her breast cancer oncologist wants to initiate neoadjuvant chemotherapy plus trastuzumab (Herceptin).

What side effects should she be concerned about particularly from the trastuzumab?

  • A) Hepatotoxicity
  • B) Cardiotoxicity
  • C) Nephrotoxicity
  • D) Neurotoxicity
  • E) Pulmonary toxicity


Serena Tharani


Dr. Raj Dasgupta