Step 2

Infectious Disease 1

A 61-year-old woman with osteopenia managed with calcium and Vitamin D supplements and hypothyroidism on levothyroxine comes to a local walk-in clinic after a potential COVID-19 exposure during the holidays. She states that she received 2 doses of the mRNA COVID vaccine but did not receive her booster dose yet. She does admit to attending a large indoor event a couple of days ago and traveling on an airplane during the hectic holiday season. She is having insomnia from the stress of possibly being COVID-19 positive. She is nervous about going back to work and appears anxious especially with the news about how contagious the Omicron variant is and wants to make sure she is not infected. Physical exam is unremarkable and the patient is asymptomatic except that while waiting to be seen, she developed a headache that she describes as a “tight band around my head.” She is very frustrated and confused about all the different tests available for SARS-CoV-2 detection but insists that she want the “best and most accurate test” to detect active infection.

What test should be offered to this patient?

  • A) SARS-CoV-2 nasal PCR swab
  • B) SARS-CoV-2 serum neutralizing antibody titer
  • C) SARS- CoV-2 rapid antigen test
  • D) No testing indicated and give her a presumptive diagnosis of COVID-19
  • E) Chest x-ray and sputum culture


Dr. Raj Dasgupta


Dr. Raj Dasgupta