Step 2

Hematology 5

A 14-year-old boy presents to his pediatrician for evaluation of recurrent epistaxis, which has been occurring more frequently over the last two years. He has no other symptoms. The patient is adopted, and his adoptive father believes the patient’s biological mother had a similar condition. Physical examination reveals mucocutaneous telangiectasias on the lips and oral mucosa. Lab tests are ordered and indicate a microcytic anemia, normal platelets, and normal creatinine.

Which of the following additional features is most likely present in this patient?

  • A) Arthralgias
  • B) Auto-antibodies versus ADAMTS-13
  • C) Hamartomatous gastrointestinal polyps
  • D) Pulmonary arteriovenous malformation
  • E) Tracheal narrowing with ulceration


Alexandra Conway


Dr. Ted O'Connell