Step 2

Gastrointestinal 8

A 37-year-old woman presents to her primary care physician for evaluation of diffuse itching accompanied by fatigue and progressive yellowing of her skin. She first noticed these symptoms 5 months ago. She does not drink alcohol or use drugs. She denies recent travel and is in a monogamous relationship with her wife of 8 years. Physical examination is significant for scleral icterus and jaundice. Labs are significant for a positive antimitochondrial antibody and an elevated alkaline phosphatase (ALP).

Which of the following is not associated with the patient’s most likely diagnosis?
  • A) Hepatocellular carcinoma
  • B) Raynaud syndrome
  • C) Sjögren syndrome
  • D) Ulcerative colitis
  • E) Xanthomas


Alexandra Conway


Dr. Ted O'Connell

Last updated

Jun 09, 2024


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