Step 2

Endocrinology 4

A 65-year-old woman presents to the clinic for an annual physical exam. She has a history of type 2 diabetes mellitus, hyperlipidemia, hypertension, and chronic kidney disease stage 3. She currently takes only metformin 1000 mg twice daily. Recent lab work includes fasting blood glucose levels 180 mg/dL and HbA1c 8.5%. Her urine albumin/creatinine ratio is >500. She is started on losartan 50 mg daily.

Which of the following medications should be added to slow the progression of chronic kidney disease in this patient?

  • A) Angiotensin-converting enzyme (ACE) inhibitor
  • B) Glucogaon-like peptide 1 (GLP-1) agonist
  • C) Loop diuretic
  • D) No other medication is indicated at this time
  • E) Sodium-glucose cotransporter-2 (SGLT2) inhibitor


Serena Tharani


Dr. Raj Dasgupta

Last updated

Feb 20, 2023

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