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Pharmacology 16

A 68-year-old woman presents to her primary care physician for her annual physical exam. Past medical history is significant for menopause at age 57. She does not take any medications. She does not smoke cigarettes or drink alcohol. , Lab work is all within normal limits. A bone mineral density test obtained prior to the appointment indicates a Z score of -2.6.

Which of the following describes the primary mechanism of action of the first-line agent to treat this patient’s osteoporosis?

  • A) Antagonism of parathyroid hormone activity
  • B) Inhibition of osteoclast activity
  • C) Monoclonal antibody directed against RANKL
  • D) Parathyroid hormone receptor agonism
  • E) Selective estrogen receptor modulation

Authors

Alexandra Conway

Editor

Dr. Ted O'Connell

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