Step 1

Microbiology 26

A 25-year-old woman is transported to the emergency department by emergency medical services with multiple injuries from a motor vehicle accident. Her vitals show blood pressure of 80/50 mm/Hg, heart rate of 150 beats/minute, and respirations of 27/minute. Physical examination shows multiple abrasions and obvious deformities of the right wrist and right knee. There is an ecchymosis of the left upper quadrant of the abdomen. A CT scan demonstrates a ruptured spleen. The patient is taken to the operating room, and she undergoes a splenectomy. After the surgery, the patient is counseled on the importance of vaccinations against encapsulated bacteria.

Through which of the following mechanisms does the spleen protect against these organisms?

  • A) Collective cord of Billroth filtration system
  • B) Fas ligands of T cells binding leading to caspase activation
  • C) Macrophage receptors recognize and bind with bacteria capsule antigen
  • D) Opsonization of bacteria with antibodies which are then phagocytosed by macrophages
  • E) Spleen lipase reacts with bacterial liposaccharides

Authors

Husban Halim

Editor

Dr. Ted O'Connell

Last updated

Oct 24, 2023

Our Other Products: