A 31-year-old woman presents at the emergency department with fever for the past two days and a burning sensation while urinating over the past few weeks. She reports having unprotected sex with multiple partners over the past six months. Past medical history is significant for eczema and asthma. She does not currently take any medications. Vital signs are temperature 37.9°C (100.2°F), blood pressure 118/74 mm Hg, pulse 94 beats/minute, and respirations 16/minute. On physical examination, purulent cervical discharge is evident and cervical motion tenderness also noted.
WWhich of the following is the most appropriate investigation for the definitive diagnosis of the most likely etiology of this patient’s symptoms?
- A) Dark field microscopy
- B) Giemsa stain and microscopy
- C) Gram staining followed by culture
- D) Nucleic acid amplification testing (NAAT)
- E) Serologic testing for antibodies