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Biochemistry 19

A 24-year-old woman is evaluated in the hospital for dyspnea, weight gain, constipation, and “feeling cold,” which have progressed over the last 3 weeks. She has been admitted to the hospital for 8 weeks for an exacerbation of Crohn disease and has been gradually improving with parenteral nutrition and immunosuppressants. Past medical history is otherwise unremarkable. Vital signs are within normal limits. Physical examination is significant only for a well-healing abrasion on her left leg that she sustained when she bumped the edge of the hospital bed while ambulating in the hospital room. Laboratory studies indicate an elevated TSH and normal glucose. Complete blood count and chemistry panel are within normal limits. Echocardiogram reveals dilated cardiomyopathy.

This patient is most likely experiencing which of the following micronutrient derangements?

  • A) Chromium deficiency
  • B) Copper deficiency
  • C) Manganese toxicity
  • D) Selenium deficiency
  • E) Zinc deficiency


Alexandra Conway


Dr. Ted O'Connell